So, when you have a file that you need to make changes to, the pdf file format is a big inconvenience. Definition of plicamycin nci drug dictionary national. Plicamycin definition plicamycin is also known as mithramycin and mithracin. Create pdf files from scratch, or merge and combine documents. Plicamycin definition of plicamycin by medical dictionary. Also, avoid other persons who have taken oral polio vaccine. A particular antibiotic drug yes, id like to receive word of the day emails from. It is also used to treat a higherthannormal amounts of calcium in the blood or urine. It has been used in the treatment of testicular cancer, pagets. Plicamycin binds to the minor groove of dna at gcrich sites, resulting in inhibition of rna synthesis.
The best quality pdf to word conversion on the market free and easy to use. Mithramycin for children and adults with solid tumors or ewing. Fr if you have any questions, comments, or concerns about the content of this page, please click here. If you have any questions about this, check with your doctor. See actual entry in rtecs for complete information. Convert pdf files to and from any microsoft office formaton the desktop with nitro pro or in any web browser with nitro cloud. Extinguishing media protective equipment and wear selfcontained breathing apparatus and protective clothing to prevent contact with skin and eyes.
Files of the type pl1 or files with the file extension. In a small number of dogs where plicamycin has been used at a low dose of 25 mgkg intravenously, calcium concentrations decreased within 12 h and remained suppressed for d. Plicamycin may lower your bodys resistance and there is a chance you might get the infection the immunization is meant to prevent. Several different structures are currently reported in different places all with the same chromomycin core, but with different. Plicamycin is also used to reduce hypercalcemia, especially that due to. Notice the selected file appears in the view window on the right.
It is useful when you want to send a document to someone and youre not sure whether that person has microsoft word. Mitomycin c investigated as a drug, mutagen, natural product, reproductive effector, and tumorigen. Fortunately, you can turn a pdf into word easily using our pdf to word converter online, which keeps all your formatting intact but. Plicamycin may also lower calcium serum levels by inhibiting the effect of parathyroid hormone upon osteoclasts or by blocking the hypercalcemic action of pharmacologic doses of vitamin d. Plicamycin, which was formerly known as mithramycin, is an antibiotic that is used as an anticancer agent in the therapy of testicular and germ cell cancers. Your session expired and your files were automatically deleted from our servers. Definition of plicamycin nci dictionary of cancer terms. Plicamycin is an antineoplastic antibiotic produced by streptomyces plicatus. Plicamycin belongs to the group of medicines known as antineoplastics. In addition, plicamycin may inhibit bone resorption by down regulating transcription of csrc, an oncogene involved in bone metabolism and resorption.
It is also used to treat hypercalcemia or hypercalciuria too much calcium in the blood or urine that may occur with some types of cancer. Plication definition of plication by medical dictionary. Find patient medical information for plicamycin injection on webmd including its uses, side effects and safety, interactions, pictures, warnings and user ratings. Plicamycin, also known as mithramycin or mithramycin a is an antibiotic isolated from the bacterium streptomyces plicatus with antineoplastic activity. What you need to convert a ply file to a pdf file or how you can create a pdf version from your ply file. It is used as a fluorescent dye and as an antineoplastic agent, especially in bone and testicular tumors. Plicamycin binds to dna and prevents cells from making rna and proteins. Plicamycin formerly mithramycin is an antiresorptive drug that was the firstline agent for treating hypercalcemia in humans for many years. Files of the type ply or files with the file extension. In addition to converting pdf to word, the service enables users to convert multiple formats to pdf, grab the contents of webpages to pdf, convert pdf files into excel spreadsheets, convert pdf files into jpg images and merge various files, including pdf files, into a single compact pdf document. Phantompdf is the pdf editor that is enterprise ready. Plicamycin intravenous route proper use mayo clinic. Use nitros industryleading pdf to word converter to create better quality doc files than the alternatives.
Convert pdf files to and from any microsoft office format. Edit any document, including images, paragraphs and pages. In addition, it may be used as treatment for hypercalcemia. Plicamycin is lethal to hela cells in 48 hours at concentrations as low as 0. A tricyclic pentaglycosidic antibiotic from streptomyces strains that inhibits rna and protein synthesis by adhering to dna. Free service for documents up to 200 pages or 50 mb and 3 tasks per hour. Edit any pdf file, including all images, paragraphs, and pages. Pdf converter is a online webbased document to pdf converter software. Convert and create pdf from various types of files like word doc, excel xls, powerpoint ppt.
Convert pdf to word free online pdf to word converter. Plicamycin may also be used for purposes other than those listed in this medication guide. In addition, other persons living in your household should not take oral polio vaccine since there is a chance they could pass the polio virus on to you. Plicamycin dictionary definition plicamycin defined. Information and translations of plicamycin in the most comprehensive dictionary definitions resource on the web. Purpose plicamycin is a drug used to treat testicular cancer in patients who are not good. However, it is very important that you continue to receive the medicine, even if you begin to feel ill. Plicamycin medical definition merriamwebster medical. Plicamycin cancer drug manual september 1994 for the patient. The retention time is about minutes for plicamycin. Plicamycin, also known as mithramycin, binds to the minor groove of dna at gcrich sites, resulting in inhibition of rna synthesis. Plicamycin is administered into a vein intravenous, and the dose depends on several factors, including the condition being treated, the size of the patient, the particular treatment regimen being used, and the overall health of the patient.
Plicamycin is also used in the treatment of treat too much calcium in the blood hypercalcemia and too much calcium in the urine hypercalciuria associated with a variety of advanced forms of cancer. Plicamycin intravenous route description and brand names. Hematologic effects including a bleeding syndrome which usually begins with an episode of epistaxis, comprise the major form of toxicity associated with the use of plicamycin. Plicamycin for injection is a sterile,dry mixture of plicamycin and mannitol. Mithracin plicamycin is a potent antineoplastic agent which has been shown to be useful in the treatment of carefully selected hospitalized patients with malignant tumors of the testis in whom successful treatment by surgery andor radiation is impossible. Plicamycin, which was formerly known as mithramycin, is an antibiotic that is used as an anticancer agent in the therapy of testicular cancer. Find the pdf, and open it you might have to select browse and find the pdf in a folder. Plicamycin sometimes causes nausea, vomiting, and loss of appetite. A pdf file is a type of file that is designed to be viewable on any computer.
Mithramycin, mithracin plicamycin plikamysin is a drug that is used to lower calcium levels in your blood. Convert pdf to word in one click with convertpdftoword. Hypercalcemia is a condition characterized by high levels of calcium in the blood. Only select registry of toxic effects of chemical substances rtecs data is presented here. Pdf files are designed for viewing rather than editing, so they are ideal for situations where you have a final version that does. Plicamycin causes acute hepatic injury that arises within days of starting therapy, but is usually transient and asymptomatic and rarely leads to jaundice. Word tells you that its going to make a copy of the pdf and convert its contents into a format that word can display. Select file open, then browse to the folder that contains your pdfs. Plicamycin for injection, chemical structure, molecular. Plicamycin is used to treat cancer of the testicles. Pdf documents include text, images, objects, and scanned pages as images, and there is no easy way to edit pdf.
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